| Specifications | Details |
| Model | MSI PRO B650M-B |
| CPU Socket | AMD Socket AM5 (Supports Ryzen™ 9000/8000/7000 Series) |
| Chipset | AMD B650 |
| Memory | 2 x DDR5 DIMM slots, Max. 96GB (up to 6800+ MHz OC) |
| Expansion Slots | 1 x PCIe 4.0 x16, 1 x PCIe 3.0 x1 |
| Storage | 1 x M.2 slot (PCIe 4.0 x4), 4 x SATA 6Gb/s ports |
| Ethernet | Realtek® RTL8125BG 2.5G LAN |
| USB (Rear) | 4 x USB 3.2 Gen 1 (Type-A), 2 x USB 2.0 |
| Video Outputs | 1 x HDMI® 2.1, 1 x VGA |
| Audio | Realtek® ALC897 Codec, 7.1-Channel HD Audio |
| Form Factor | Micro-ATX (215 mm x 243.84 mm) |
